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Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming

BACKGROUND: A multitude of recent studies has observed common epigenetic changes develop in tumour cells of multiple lineages following exposure to stresses such as hypoxia, chemotherapeutics, immunotherapy or targeted therapies. A significant increase in the transcriptionally repressive mark trimet...

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Detalles Bibliográficos
Autores principales: Torrano, Joachim, Al Emran, Abdullah, Hammerlindl, Heinz, Schaider, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408861/
https://www.ncbi.nlm.nih.gov/pubmed/30850015
http://dx.doi.org/10.1186/s13148-019-0644-y