Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation

OBJECTIVES: To investigate the protective effect of ginsenoside Rg1 on relieving sepsis-induced lung inflammation and injury in vivo and in vitro. METHODS: Cultured human pulmonary epithelial cell line A549 was challenged with LPS to induce cell injury, and CLP mouse model was generated to mimic cli...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qian-Lu, Yang, Lei, Peng, Yue, Gao, Min, Yang, Ming-Shi, Xing, Wei, Xiao, Xian-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409002/
https://www.ncbi.nlm.nih.gov/pubmed/30918470
http://dx.doi.org/10.1155/2019/6453296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409002/
https://www.ncbi.nlm.nih.gov/pubmed/30918470
http://dx.doi.org/10.1155/2019/6453296

Ejemplares similares