Cargando…

Ginsenoside Rg1 Regulates SIRT1 to Ameliorate Sepsis-Induced Lung Inflammation and Injury via Inhibiting Endoplasmic Reticulum Stress and Inflammation

OBJECTIVES: To investigate the protective effect of ginsenoside Rg1 on relieving sepsis-induced lung inflammation and injury in vivo and in vitro. METHODS: Cultured human pulmonary epithelial cell line A549 was challenged with LPS to induce cell injury, and CLP mouse model was generated to mimic cli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qian-Lu, Yang, Lei, Peng, Yue, Gao, Min, Yang, Ming-Shi, Xing, Wei, Xiao, Xian-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409002/ https://www.ncbi.nlm.nih.gov/pubmed/30918470 http://dx.doi.org/10.1155/2019/6453296

Ejemplares similares

Ginsenoside Rg1 ameliorates diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress‐induced apoptosis in a streptozotocin‐induced diabetes rat model
por: Yu, Haitao, et al.
Publicado: (2016)

Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats
por: Qin, Qiaoji, et al.
Publicado: (2019)

Ginsenoside Rg3 ameliorates allergic airway inflammation and oxidative stress in mice
por: Huang, Wen-Chung, et al.
Publicado: (2021)

Ginsenoside Rg1 Prevents Doxorubicin-Induced Cardiotoxicity through the Inhibition of Autophagy and Endoplasmic Reticulum Stress in Mice
por: Xu, Zhi-Meng, et al.
Publicado: (2018)

20(S)-Ginsenoside Rg2 attenuates myocardial ischemia/reperfusion injury by reducing oxidative stress and inflammation: role of SIRT1
por: Fu, Wenwen, et al.
Publicado: (2018)

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy
por: Wang, Ni, et al.
Publicado: (2023)

Amelioration of insulin resistance by Rk(1) + Rg(5) complex under endoplasmic reticulum stress conditions
por: Ponnuraj, Shree Priya, et al.
Publicado: (2014)

Ginsenoside Rg3 alleviates inflammation in a rat model of myocardial infarction via the SIRT1/NF-κB pathway
por: Tu, Chenchen, et al.
Publicado: (2020)

Preconditioning with Endoplasmic Reticulum Stress Ameliorates Endothelial Cell Inflammation
por: Leonard, Antony, et al.
Publicado: (2014)

Metabolism of 20(S)-Ginsenoside Rg(2) by Rat Liver Microsomes: Bioactivation to SIRT1-Activating Metabolites
por: Ma, Li-Yuan, et al.
Publicado: (2016)

Ginsenoside Rg5 Ameliorates Cisplatin-Induced Nephrotoxicity in Mice through Inhibition of Inflammation, Oxidative Stress, and Apoptosis
por: Li, Wei, et al.
Publicado: (2016)

Ginsenoside Rg1 Ameliorates Palmitic Acid-Induced Hepatic Steatosis and Inflammation in HepG2 Cells via the AMPK/NF-κB Pathway
por: Xiao, Qing, et al.
Publicado: (2019)

Antitumor effect of ginsenoside Rg3 on gallbladder cancer by inducing endoplasmic reticulum stress-mediated apoptosis in vitro and in vivo
por: Wu, Keren, et al.
Publicado: (2018)

Ginsenoside Rg3 alleviates septic liver injury by regulating the lncRNA TUG1/miR-200c-3p/SIRT1 axis
por: Wu, Pan, et al.
Publicado: (2021)

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
por: Mohanan, Padmanaban, et al.
Publicado: (2018)

Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress
por: Jia, Yifan, et al.
Publicado: (2018)

Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression
por: Wang, Huiqin, et al.
Publicado: (2021)

Ginsenoside Rg3 attenuates sepsis-induced injury and mitochondrial dysfunction in liver via AMPK-mediated autophagy flux
por: Xing, Wei, et al.
Publicado: (2017)

Ginsenoside Rg1 Improves Inflammation and Autophagy of the Pancreas and Spleen in Streptozotocin-Induced Type 1 Diabetic Mice
por: Zong, Yi, et al.
Publicado: (2023)

Forsythiaside A ameliorates sepsis-induced acute kidney injury via anti-inflammation and antiapoptotic effects by regulating endoplasmic reticulum stress
por: Chen, Yi, et al.
Publicado: (2023)

Ginsenoside Rg1 Ameliorates Rat Myocardial Ischemia-Reperfusion Injury by Modulating Energy Metabolism Pathways
por: Li, Lin, et al.
Publicado: (2018)

Ginsenoside Rg2 Ameliorates Myocardial Ischemia/Reperfusion Injury by Regulating TAK1 to Inhibit Necroptosis
por: Li, Yao, et al.
Publicado: (2022)

Ginsenoside Rg1 Ameliorates Pancreatic Injuries via the AMPK/mTOR Pathway in vivo and in vitro
por: Chen, Jin, et al.
Publicado: (2023)

Ginsenoside Rg(3) promotes inflammation resolution through M2 macrophage polarization
por: Kang, Saeromi, et al.
Publicado: (2018)

Portulaca oleracea L. Extract Ameliorates Intestinal Inflammation by Regulating Endoplasmic Reticulum Stress and Autophagy
por: Zhang, Ziwei, et al.
Publicado: (2022)

Ginsenoside Rg1 regulates autophagy and endoplasmic reticulum stress via the AMPK/mTOR and PERK/ATF4/CHOP pathways to alleviate alcohol-induced myocardial injury
por: Tian, Ge, et al.
Publicado: (2023)

Ginsenoside Rg1 Ameliorates Cigarette Smoke-Induced Airway Fibrosis by Suppressing the TGF-β1/Smad Pathway In Vivo and In Vitro
por: Guan, Sibin, et al.
Publicado: (2017)

Ginsenoside Rg1 Ameliorates Acute Renal Ischemia/Reperfusion Injury via Upregulating AMPKα1 Expression
por: Zhou, Qing, et al.
Publicado: (2022)

FGF21 attenuates high uric acid-induced endoplasmic reticulum stress, inflammation and vascular endothelial cell dysfunction by activating Sirt1
por: Ouyang, Rong, et al.
Publicado: (2022)

Tanshinone IIA ameliorates Aβ transendothelial transportation through SIRT1-mediated endoplasmic reticulum stress
por: Wan, Can, et al.
Publicado: (2023)

Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage
por: Ni, X.J., et al.
Publicado: (2017)

Effects of Ginsenoside Rg1 on the Biological Activity of Human Periodontal Ligament Cells
por: Yang, Qian, et al.
Publicado: (2022)

20(S)-Ginsenoside Rg3 Protects Kidney from Diabetic Kidney Disease via Renal Inflammation Depression in Diabetic Rats
por: Zhou, Tong, et al.
Publicado: (2020)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Ginsenoside Rg3 Improves Cardiac Function after Myocardial Ischemia/Reperfusion via Attenuating Apoptosis and Inflammation
por: Zhang, Li-ping, et al.
Publicado: (2016)

Ginsenoside Rg1 Ameliorates Behavioral Abnormalities and Modulates the Hippocampal Proteomic Change in Triple Transgenic Mice of Alzheimer's Disease
por: Nie, Lulin, et al.
Publicado: (2017)

Ginsenoside Rg1 inhibits nucleus pulposus cell apoptosis, inflammation and extracellular matrix degradation via the YAP1/TAZ pathway in rats with intervertebral disc degeneration
por: Yang, Yong-hua, et al.
Publicado: (2022)

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901
por: Yang, Qing, et al.
Publicado: (2020)

A Critical Regulation of Th17 Cell Responses and Autoimmune Neuro-Inflammation by Ginsenoside Rg3
por: Park, Young-Jun, et al.
Publicado: (2020)

Ginsenoside-Rg1 Rescues Stress-Induced Depression-Like Behaviors via Suppression of Oxidative Stress and Neural Inflammation in Rats
por: Li, Ye, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e2o2elo304prvphcb3akqggm5r