Santacruzamate A Ameliorates AD-Like Pathology by Enhancing ER Stress Tolerance Through Regulating the Functions of KDELR and Mia40-ALR in vivo and in vitro

Aggregated amyloid-β protein (Aβ) and Aβ-induced neuronal apoptosis have been implicated as critical factors in the pathophysiology of Alzheimer’s disease (AD). Certain preclinical results have indicated that the increased accumulation of protein aggregates in AD-affected neurons activates the unfol...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Liu, Yue-cheng, Tan, Hui, Zhang, Yuan, Xu, Ji, Liu, Wen-lan, Li, Zong-yang, Li, Wei-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409322/
https://www.ncbi.nlm.nih.gov/pubmed/30886573
http://dx.doi.org/10.3389/fncel.2019.00061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409322/
https://www.ncbi.nlm.nih.gov/pubmed/30886573
http://dx.doi.org/10.3389/fncel.2019.00061

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