Cargando…

Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade

Molecular determinants underlying interferon (IFN)-macrophage biology can help delineate enzyme systems, pathways and mechanisms for enabling host-directed therapeutic approaches against infection. Notably, while the IFN antiviral response is known to be directly coupled to mevalonate-sterol biosynt...

Descripción completa

Detalles Bibliográficos
Autores principales: Dantoft, Widad, Robertson, Kevin A., Watkins, W. John, Strobl, Birgit, Ghazal, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409323/
https://www.ncbi.nlm.nih.gov/pubmed/30886604
http://dx.doi.org/10.3389/fmicb.2019.00355