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Structure-Based Peptide Inhibitor Design of Amyloid-β Aggregation

Many human neurodegenerative diseases are associated with amyloid fibril formation. Inhibition of amyloid formation is of importance for therapeutics of the related diseases. However, the development of selective potent amyloid inhibitors remains challenging. Here based on the structures of amyloid...

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Detalles Bibliográficos
Autores principales: Lu, Jinxia, Cao, Qin, Wang, Chuchu, Zheng, Jing, Luo, Feng, Xie, Jingfei, Li, Yichen, Ma, Xiaojuan, He, Lin, Eisenberg, David, Nowick, James, Jiang, Lin, Li, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409328/
https://www.ncbi.nlm.nih.gov/pubmed/30886570
http://dx.doi.org/10.3389/fnmol.2019.00054