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Optical Quantal Analysis Using Ca(2+) Indicators: A Robust Method for Assessing Transmitter Release Probability at Excitatory Synapses by Imaging Single Glutamate Release Events

Despite evidence that presynaptic efficacy and plasticity influence circuit function and behavior in vivo, studies of presynaptic function remain challenging owing to the difficulty of assessing transmitter release in intact tissue. Electrophysiological analyses of transmitter release are indirect a...

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Detalles Bibliográficos
Autores principales: Padamsey, Zahid, Tong, Rudi, Emptage, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409341/
https://www.ncbi.nlm.nih.gov/pubmed/30886576
http://dx.doi.org/10.3389/fnsyn.2019.00005