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Local Antigen Encounter Is Essential for Establishing Persistent CD8(+) T-Cell Memory in the CNS

While the brain is considered an immune-privileged site, the CNS may nevertheless be the focus of immune mediated inflammation in the case of infection and certain autoimmune diseases, e.g., multiple sclerosis. As in other tissues, it has been found that acute T-cell infiltration may be followed by...

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Detalles Bibliográficos
Autores principales: Schøller, Amalie S., Fonnes, Masja, Nazerai, Loulieta, Christensen, Jan P., Thomsen, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409353/
https://www.ncbi.nlm.nih.gov/pubmed/30886617
http://dx.doi.org/10.3389/fimmu.2019.00351