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Induction of Mesoderm and Neural Crest-Derived Pericytes from Human Pluripotent Stem Cells to Study Blood-Brain Barrier Interactions

In the CNS, perivascular cells (“pericytes”) associate with endothelial cells to mediate the formation of tight junctions essential to the function of the blood-brain barrier (BBB). The BBB protects the CNS by regulating the flow of nutrients and toxins into and out of the brain. BBB dysfunction has...

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Detalles Bibliográficos
Autores principales: Faal, Tannaz, Phan, Duc T.T., Davtyan, Hayk, Scarfone, Vanessa M., Varady, Erika, Blurton-Jones, Mathew, Hughes, Christopher C.W., Inlay, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409424/
https://www.ncbi.nlm.nih.gov/pubmed/30745035
http://dx.doi.org/10.1016/j.stemcr.2019.01.005