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Methods for Estimating Demography and Detecting Between-Locus Differences in the Effective Population Size and Mutation Rate

It is known that the effective population size (N(e)) and the mutation rate (u) vary across the genome. Here, we show that ignoring this heterogeneity may lead to biased estimates of past demography. To solve the problem, we develop new methods for jointly inferring past changes in population size a...

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Detalles Bibliográficos
Autores principales: Zeng, Kai, Jackson, Benjamin C, Barton, Henry J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409433/
https://www.ncbi.nlm.nih.gov/pubmed/30428070
http://dx.doi.org/10.1093/molbev/msy212