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Methods for Estimating Demography and Detecting Between-Locus Differences in the Effective Population Size and Mutation Rate
It is known that the effective population size (N(e)) and the mutation rate (u) vary across the genome. Here, we show that ignoring this heterogeneity may lead to biased estimates of past demography. To solve the problem, we develop new methods for jointly inferring past changes in population size a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409433/ https://www.ncbi.nlm.nih.gov/pubmed/30428070 http://dx.doi.org/10.1093/molbev/msy212 |