Cargando…

In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids

It has been challenging to generate in vitro models of alveolar lung diseases, as the stable culture of alveolar type 2 (AT2) cells has been difficult. Methods of generating and expanding AT2 cells derived from induced pluripotent stem cells (iPSCs) have been established and are expected to be appli...

Descripción completa

Detalles Bibliográficos
Autores principales: Korogi, Yohei, Gotoh, Shimpei, Ikeo, Satoshi, Yamamoto, Yuki, Sone, Naoyuki, Tamai, Koji, Konishi, Satoshi, Nagasaki, Tadao, Matsumoto, Hisako, Ito, Isao, Chen-Yoshikawa, Toyofumi F., Date, Hiroshi, Hagiwara, Masatoshi, Asaka, Isao, Hotta, Akitsu, Mishima, Michiaki, Hirai, Toyohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409438/
https://www.ncbi.nlm.nih.gov/pubmed/30773483
http://dx.doi.org/10.1016/j.stemcr.2019.01.014