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A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells

The transplantation of human embryonic stem cell (hESC)-derived insulin-producing β cells for the treatment of diabetes is finally approaching the clinical stage. However, even with state-of-the-art differentiation protocols, a significant percentage of undefined non-endocrine cell types are still g...

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Detalles Bibliográficos
Autores principales: Qadir, Mirza Muhammad Fahd, Álvarez-Cubela, Silvia, Belle, Kinsley, Sapir, Tamar, Messaggio, Fanuel, Johnson, Kevin B., Umland, Oliver, Hardin, Darrell, Klein, Dagmar, Pérez-Álvarez, Ingrid, Sadiq, Fatima, Alcázar, Oscar, Inverardi, Luca A., Ricordi, Camillo, Buchwald, Peter, Fraker, Christopher A., Pastori, Ricardo L., Domínguez-Bendala, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409439/
https://www.ncbi.nlm.nih.gov/pubmed/30773486
http://dx.doi.org/10.1016/j.stemcr.2019.01.012