Sphingomyelin Depletion from Plasma Membranes of Human Airway Epithelial Cells Completely Abrogates the Deleterious Actions of S. aureus Alpha-Toxin

Interaction of Staphylococcus aureus alpha-toxin (hemolysin A, Hla) with eukaryotic cell membranes is mediated by proteinaceous receptors and certain lipid domains in host cell plasma membranes. Hla is secreted as a 33 kDa monomer that forms heptameric transmembrane pores whose action compromises ma...

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Detalles Bibliográficos
Autores principales: Ziesemer, Sabine, Möller, Nils, Nitsch, Andreas, Müller, Christian, Beule, Achim G., Hildebrandt, Jan-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409578/
https://www.ncbi.nlm.nih.gov/pubmed/30791542
http://dx.doi.org/10.3390/toxins11020126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409578/
https://www.ncbi.nlm.nih.gov/pubmed/30791542
http://dx.doi.org/10.3390/toxins11020126

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