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Sphingomyelin Depletion from Plasma Membranes of Human Airway Epithelial Cells Completely Abrogates the Deleterious Actions of S. aureus Alpha-Toxin

Interaction of Staphylococcus aureus alpha-toxin (hemolysin A, Hla) with eukaryotic cell membranes is mediated by proteinaceous receptors and certain lipid domains in host cell plasma membranes. Hla is secreted as a 33 kDa monomer that forms heptameric transmembrane pores whose action compromises ma...

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Detalles Bibliográficos
Autores principales:	Ziesemer, Sabine, Möller, Nils, Nitsch, Andreas, Müller, Christian, Beule, Achim G., Hildebrandt, Jan-Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409578/ https://www.ncbi.nlm.nih.gov/pubmed/30791542 http://dx.doi.org/10.3390/toxins11020126

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