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Improved Pharmacokinetics of Icariin (ICA) within Formulation of PEG-PLLA/PDLA-PNIPAM Polymeric Micelles

Icariin (ICA) is a major flavonoid that contains the active compound Epimedii Folium. However, ICA’s pharmacokinetic characteristics remain unsatisfactory due to its low bioavailability, and hence limited drugability. In order to improve its pharmacokinetics and achieve prolonged blood circulation t...

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Detalles Bibliográficos
Autores principales: Han, Lu-Ying, Wu, Yun-Long, Zhu, Chun-Yan, Wu, Cai-Sheng, Yang, Chun-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409701/
https://www.ncbi.nlm.nih.gov/pubmed/30691070
http://dx.doi.org/10.3390/pharmaceutics11020051