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Improved Pharmacokinetics of Icariin (ICA) within Formulation of PEG-PLLA/PDLA-PNIPAM Polymeric Micelles
Icariin (ICA) is a major flavonoid that contains the active compound Epimedii Folium. However, ICA’s pharmacokinetic characteristics remain unsatisfactory due to its low bioavailability, and hence limited drugability. In order to improve its pharmacokinetics and achieve prolonged blood circulation t...
Autores principales: | Han, Lu-Ying, Wu, Yun-Long, Zhu, Chun-Yan, Wu, Cai-Sheng, Yang, Chun-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409701/ https://www.ncbi.nlm.nih.gov/pubmed/30691070 http://dx.doi.org/10.3390/pharmaceutics11020051 |
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