Amorphisation of Free Acid Ibuprofen and Other Profens in Mixtures with Nanocellulose: Dry Powder Formulation Strategy for Enhanced Solubility

The formulation of arylpropionic acid derivatives (profens), which are poorly soluble Biopharmaceutical Classification System (BCS) Type II drugs, has a strong impact on their therapeutic action. This article shows that heat-treated powder mixtures of free acid profens with high surface area Cladoph...

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Detalles Bibliográficos
Autores principales: Mantas, Athanasios, Labbe, Valentine, Loryan, Irena, Mihranyan, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409705/
https://www.ncbi.nlm.nih.gov/pubmed/30736357
http://dx.doi.org/10.3390/pharmaceutics11020068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409705/
https://www.ncbi.nlm.nih.gov/pubmed/30736357
http://dx.doi.org/10.3390/pharmaceutics11020068

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