A Noninvasive Comparison Study between Human Gliomas with IDH1 and IDH2 Mutations by MR Spectroscopy

The oncogenes that are expressed in gliomas reprogram particular pathways of glucose, amino acids, and fatty acid metabolism. Mutations in isocitrate dehydrogenase genes (IDH1/2) in diffuse gliomas are associated with abnormally high levels of 2-hydroxyglutarate (2-HG) levels. The aim of this study...

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Detalles Bibliográficos
Autores principales: Shen, Xin, Voets, Natalie L., Larkin, Sarah J., de Pennington, Nick, Plaha, Puneet, Stacey, Richard, McCullagh, James S. O., Schofield, Christopher J., Clare, Stuart, Jezzard, Peter, Cadoux-Hudson, Tom, Ansorge, Olaf, Emir, Uzay E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409728/
https://www.ncbi.nlm.nih.gov/pubmed/30791611
http://dx.doi.org/10.3390/metabo9020035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409728/
https://www.ncbi.nlm.nih.gov/pubmed/30791611
http://dx.doi.org/10.3390/metabo9020035

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