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Modeling Host-Virus Interactions in Viral Infectious Diseases Using Stem-Cell-Derived Systems and CRISPR/Cas9 Technology

Pathologies induced by viral infections have undergone extensive study, with traditional model systems such as two-dimensional (2D) cell cultures and in vivo mouse models contributing greatly to our understanding of host-virus interactions. However, the technical limitations inherent in these system...

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Detalles Bibliográficos
Autores principales: Kim, Jihoon, Koo, Bon-Kyoung, Yoon, Ki-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409779/
https://www.ncbi.nlm.nih.gov/pubmed/30704043
http://dx.doi.org/10.3390/v11020124