Development and Application of Immunoaffinity Column Purification and Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry for Determination of Domoic Acid in Shellfish

Domoic acid (DA) is a neurotoxin associated with amnesic shellfish poisoning (ASP). Though LC coupled to tandem mass spectrometry (LC-MS/MS) has become the preferred method for DA determination, traditional sample pretreatment is still labor-intensive. In this study, a simple, efficient and selectiv...

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Detalles Bibliográficos
Autores principales: Chen, Si, Zhang, Xiaojun, Yan, Zhongyong, Hu, Yangyang, Lu, Yibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409838/
https://www.ncbi.nlm.nih.gov/pubmed/30717167
http://dx.doi.org/10.3390/toxins11020083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409838/
https://www.ncbi.nlm.nih.gov/pubmed/30717167
http://dx.doi.org/10.3390/toxins11020083

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