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Development and Application of Immunoaffinity Column Purification and Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry for Determination of Domoic Acid in Shellfish

Domoic acid (DA) is a neurotoxin associated with amnesic shellfish poisoning (ASP). Though LC coupled to tandem mass spectrometry (LC-MS/MS) has become the preferred method for DA determination, traditional sample pretreatment is still labor-intensive. In this study, a simple, efficient and selectiv...

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Detalles Bibliográficos
Autores principales:	Chen, Si, Zhang, Xiaojun, Yan, Zhongyong, Hu, Yangyang, Lu, Yibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409838/ https://www.ncbi.nlm.nih.gov/pubmed/30717167 http://dx.doi.org/10.3390/toxins11020083

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