Mutagenesis of α-Conotoxins for Enhancing Activity and Selectivity for Nicotinic Acetylcholine Receptors

Nicotinic acetylcholine receptors (nAChRs) are found throughout the mammalian body and have been studied extensively because of their implication in a myriad of diseases. α-Conotoxins (α-CTxs) are peptide neurotoxins found in the venom of marine snails of genus Conus. α-CTxs are potent and selective...

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Detalles Bibliográficos
Autores principales: Turner, Matthew W., Marquart, Leanna A., Phillips, Paul D., McDougal, Owen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409848/
https://www.ncbi.nlm.nih.gov/pubmed/30781866
http://dx.doi.org/10.3390/toxins11020113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409848/
https://www.ncbi.nlm.nih.gov/pubmed/30781866
http://dx.doi.org/10.3390/toxins11020113

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