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Automated Nuclear Cartography Reveals Conserved Sperm Chromosome Territory Localization across 2 Million Years of Mouse Evolution

Measurements of nuclear organization in asymmetric nuclei in 2D images have traditionally been manual. This is exemplified by attempts to measure chromosome position in sperm samples, typically by dividing the nucleus into zones, and manually scoring which zone a fluorescence in-situ hybridisation (...

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Detalles Bibliográficos
Autores principales: Skinner, Benjamin Matthew, Bacon, Joanne, Rathje, Claudia Cattoni, Larson, Erica Lee, Kopania, Emily Emiko Konishi, Good, Jeffrey Martin, Affara, Nabeel Ahmed, Ellis, Peter James Ivor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409866/
https://www.ncbi.nlm.nih.gov/pubmed/30717218
http://dx.doi.org/10.3390/genes10020109