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Cytotoxic Effects of Some Flavonoids and Imatinib on the K562 Chronic Myeloid Leukemia Cell Line: Data Analysis Using the Combination Index Method

BACKGROUND: Flavonoids are natural compounds with antioxidant, anticarcinogenic, and anti-inflammatory effects. AIMS: To determine the cytotoxic effects of flavonoids and drug resistance related to P-gp on K562 human chronic myeloid leukemia cells. We also aimed to evaluate the therapeutic potential...

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Detalles Bibliográficos
Autores principales: Danışman Kalındemirtaş, Ferdane, Birman, Hüsniye, Candöken, Eda, Bilgiç Gazioğlu, Sema, Melikoğlu, Gülay, Kuruca, Serap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409953/
https://www.ncbi.nlm.nih.gov/pubmed/30396879
http://dx.doi.org/10.4274/balkanmedj.galenos.2018.2017.1244