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Polymer Distribution and Mechanism Conversion in Multiple Media of Phase-Separated Controlled-Release Film-Coating

Phase-separated films of water-insoluble ethyl cellulose (EC) and water-soluble hydroxypropyl cellulose (HPC) can be utilized to tailor drug release from coated pellets. In the present study, the effects of HPC levels and the pH, type, ionic strength and osmolarity of the media on the release profil...

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Detalles Bibliográficos
Autores principales: Chen, Lu, Yang, Guobao, Chu, Xiaoyang, Gao, Chunhong, Wang, Yuli, Gong, Wei, Li, Zhiping, Yang, Yang, Yang, Meiyan, Gao, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410001/
https://www.ncbi.nlm.nih.gov/pubmed/30769846
http://dx.doi.org/10.3390/pharmaceutics11020080