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Long-Lasting, Antinociceptive Effects of pH-Sensitive Niosomes Loaded with Ibuprofen in Acute and Chronic Models of Pain

Ibuprofen is one of the non-steroidal anti-inflammatory drugs (NSAIDs) widely used to treat pain conditions. NSAIDs encounter several obstacles to passing across biological membranes. To overcome these constraints, we decided to study the effects of a new pH-sensitive formulation of niosomes contain...

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Detalles Bibliográficos
Autores principales: Marzoli, Francesca, Marianecci, Carlotta, Rinaldi, Federica, Passeri, Daniele, Rossi, Marco, Minosi, Paola, Carafa, Maria, Pieretti, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410004/
https://www.ncbi.nlm.nih.gov/pubmed/30717144
http://dx.doi.org/10.3390/pharmaceutics11020062