N(6)-Methyladenosine Landscape of Glioma Stem-Like Cells: METTL3 Is Essential for the Expression of Actively Transcribed Genes and Sustenance of the Oncogenic Signaling

Despite recent advances in N(6)-methyladenosine (m(6)A) biology, the regulation of crucial RNA processing steps by the RNA methyltransferase-like 3 (METTL3) in glioma stem-like cells (GSCs) remains obscure. An integrated analysis of m(6)A-RIP (RNA immunoprecipitation) and total RNA-Seq of METTL3-sil...

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Detalles Bibliográficos
Autores principales: Visvanathan, Abhirami, Patil, Vikas, Abdulla, Shibla, Hoheisel, Jörg D., Somasundaram, Kumaravel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410051/
https://www.ncbi.nlm.nih.gov/pubmed/30781903
http://dx.doi.org/10.3390/genes10020141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410051/
https://www.ncbi.nlm.nih.gov/pubmed/30781903
http://dx.doi.org/10.3390/genes10020141

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