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Development of Solid Lipid Nanoparticles by Cold Dilution of Microemulsions: Curcumin Loading, Preliminary In Vitro Studies, and Biodistribution

Background: Solid lipid nanoparticles (SLNs) are attractive drug delivery systems for lipophilic molecules like curcumin (CURC) with low chemical stability. Methods: A simple, innovative, and cold-operating method, named “cold dilution of microemulsion” is developed by the authors to produce SLNs. A...

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Detalles Bibliográficos
Autores principales: Chirio, Daniela, Peira, Elena, Dianzani, Chiara, Muntoni, Elisabetta, Gigliotti, Casimiro Luca, Ferrara, Benedetta, Sapino, Simona, Chindamo, Giulia, Gallarate, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410061/
https://www.ncbi.nlm.nih.gov/pubmed/30744025
http://dx.doi.org/10.3390/nano9020230