Predicting Blood–Brain Barrier Permeability of Marine-Derived Kinase Inhibitors Using Ensemble Classifiers Reveals Potential Hits for Neurodegenerative Disorders

The recent success of small-molecule kinase inhibitors as anticancer drugs has generated significant interest in their application to other clinical areas, such as disorders of the central nervous system (CNS). However, most kinase inhibitor drug candidates investigated to date have been ineffective...

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Detalles Bibliográficos
Autores principales: Plisson, Fabien, Piggott, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410078/
https://www.ncbi.nlm.nih.gov/pubmed/30699889
http://dx.doi.org/10.3390/md17020081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410078/
https://www.ncbi.nlm.nih.gov/pubmed/30699889
http://dx.doi.org/10.3390/md17020081

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