Formulation Strategies to Improve Nose-to-Brain Delivery of Donepezil

Donepezil (DPZ) is widely used in the treatment of Alzheimer’s disease in tablet form for oral administration. The pharmacological efficacy of this drug can be enhanced by the use of intranasal administration because this route makes bypassing the blood–brain barrier (BBB) possible. The aim of this...

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Detalles Bibliográficos
Autores principales: Espinoza, Lupe Carolina, Silva-Abreu, Marcelle, Clares, Beatriz, Rodríguez-Lagunas, María José, Halbaut, Lyda, Cañas, María-Alexandra, Calpena, Ana Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410084/
https://www.ncbi.nlm.nih.gov/pubmed/30717264
http://dx.doi.org/10.3390/pharmaceutics11020064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410084/
https://www.ncbi.nlm.nih.gov/pubmed/30717264
http://dx.doi.org/10.3390/pharmaceutics11020064

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