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On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway

DNA replication in eukaryotes is achieved by the activation of multiple replication origins which needs to be precisely coordinated in space and time. This spatio-temporal replication program is regulated by many factors to maintain genome stability, which is frequently threatened through stresses o...

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Detalles Bibliográficos
Autores principales: Ciardo, Diletta, Goldar, Arach, Marheineke, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410103/
https://www.ncbi.nlm.nih.gov/pubmed/30700024
http://dx.doi.org/10.3390/genes10020094