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On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway
DNA replication in eukaryotes is achieved by the activation of multiple replication origins which needs to be precisely coordinated in space and time. This spatio-temporal replication program is regulated by many factors to maintain genome stability, which is frequently threatened through stresses o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410103/ https://www.ncbi.nlm.nih.gov/pubmed/30700024 http://dx.doi.org/10.3390/genes10020094 |