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Enhancing PD-1 Gene Silence in T Lymphocytes by Comparing the Delivery Performance of Two Inorganic Nanoparticle Platforms

Suitable carriers are crucial to RNAi applications for cancer genotherapy and T-cell immunotherapy. In this research, we selected two extensively-investigated biocompatible inorganic nanoparticle carriers, i.e., layered double hydroxide (LDH) and lipid-coated calcium phosphate (LCP) and then compare...

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Detalles Bibliográficos
Autores principales: Wu, Yanheng, Gu, Wenyi, Li, Li, Chen, Chen, Xu, Zhi Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410115/
https://www.ncbi.nlm.nih.gov/pubmed/30696033
http://dx.doi.org/10.3390/nano9020159