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Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir

The 2014 Ebolavirus outbreak in West Africa highlighted the need for vaccines and therapeutics to prevent and treat filovirus infections. A well-characterized small animal model that is susceptible to wild-type filoviruses would facilitate the screening of anti-filovirus agents. To that end, we char...

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Detalles Bibliográficos
Autores principales: Comer, Jason E., Escaffre, Olivier, Neef, Natasha, Brasel, Trevor, Juelich, Terry L., Smith, Jennifer K., Smith, Jeanon, Kalveram, Birte, Perez, David D., Massey, Shane, Zhang, Lihong, Freiberg, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410141/
https://www.ncbi.nlm.nih.gov/pubmed/30717492
http://dx.doi.org/10.3390/v11020137