THO Complex Subunit 7 Homolog Negatively Regulates Cellular Antiviral Response against RNA Viruses by Targeting TBK1

RNA virus invasion induces a cytosolic RIG-I-like receptor (RLR) signaling pathway by promoting assembly of the Mitochondrial antiviral-signaling protein (MAVS) signalosome and triggers the rapid production of type I interferons (IFNs) and proinflammatory cytokines. During this process, the pivotal...

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Detalles Bibliográficos
Autores principales: He, Tian-Sheng, Xie, Tao, Li, Jing, Yang, Ya-Xian, Li, Changsheng, Wang, Weiying, Cao, Lingzhen, Rao, Hua, Ju, Cynthia, Xu, Liang-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410154/
https://www.ncbi.nlm.nih.gov/pubmed/30769920
http://dx.doi.org/10.3390/v11020158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410154/
https://www.ncbi.nlm.nih.gov/pubmed/30769920
http://dx.doi.org/10.3390/v11020158

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