Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents

Triterpenoid saponins from Saponinum album (SA) significantly augment the cytotoxicity of saporin-based immunotoxins but the mechanism of augmentation is not fully understood. We investigated the effects of six small molecule pharmacological agents, which interfere with endocytic and other processes...

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Detalles Bibliográficos
Autores principales: Smith, Wendy S., Johnston, David A., Holmes, Suzanne E., Wensley, Harrison J., Flavell, Sopsamorn U., Flavell, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410249/
https://www.ncbi.nlm.nih.gov/pubmed/30791598
http://dx.doi.org/10.3390/toxins11020127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410249/
https://www.ncbi.nlm.nih.gov/pubmed/30791598
http://dx.doi.org/10.3390/toxins11020127

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