Cargando…

Investigating the DNA-Binding Site for VirB, a Key Transcriptional Regulator of Shigella Virulence Genes, Using an In Vivo Binding Tool

The transcriptional anti-silencing and DNA-binding protein, VirB, is essential for the virulence of Shigella species and, yet, sequences required for VirB-DNA binding are poorly understood. While a 7-8 bp VirB-binding site has been proposed, it was derived from studies at a single VirB-dependent pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Karney, Monika M.A., McKenna, Joy A., Weatherspoon-Griffin, Natasha, Karabachev, Alexander D., Millar, Makensie E., Potocek, Eliese A., Wing, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410309/
https://www.ncbi.nlm.nih.gov/pubmed/30781432
http://dx.doi.org/10.3390/genes10020149