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MnTE-2-PyP Attenuates TGF-β-Induced Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Inhibiting the Smad2/3 Signaling Pathway

BACKGROUND: As a key step in enhancing cancer cell invasion and metastasis, epithelial-mesenchymal transition (EMT) plays an important role in colorectal cancer progression. EMT is triggered by a variety of signaling pathways, among which the transforming growth factor β (TGF-β) signaling pathway ha...

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Detalles Bibliográficos
Autores principales: Yang, Yu, Zhang, Pei, Yan, Ruicheng, Wang, Qi, Fang, Erhu, Wu, Hongxue, Li, Shijun, Tan, Haiyan, Zhou, Xing, Ma, Xianxiong, Tang, Yu, Huang, Yongming, Deng, Rui, Liu, Ying, Tong, Shilun, Wang, Zhihua, Oberley-Deegan, Rebecca E., Tong, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410463/
https://www.ncbi.nlm.nih.gov/pubmed/30931081
http://dx.doi.org/10.1155/2019/8639791