Down-regulation of FZD3 receptor suppresses growth and metastasis of human melanoma independently of canonical WNT signaling

Frizzled 3 receptor (FZD3) plays an important role in the homeostasis of the neural crest and its derivatives, which give rise to pigment-synthesizing cells, melanocytes. While the role for FZD3 in specification of the melanocytic lineage from neural crest is well established, its significance in th...

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Detalles Bibliográficos
Autores principales: Li, Chen, Nguyen, Vincent, Clark, Kaitlyn N., Zahed, Tara, Sharkas, Shawn, Filipp, Fabian V., Boiko, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410844/
https://www.ncbi.nlm.nih.gov/pubmed/30792348
http://dx.doi.org/10.1073/pnas.1813802116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410844/
https://www.ncbi.nlm.nih.gov/pubmed/30792348
http://dx.doi.org/10.1073/pnas.1813802116

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