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H5N8 and H7N9 packaging signals constrain HA reassortment with a seasonal H3N2 influenza A virus

Influenza A virus (IAV) has a segmented genome, which (i) allows for exchange of gene segments in coinfected cells, termed reassortment, and (ii) necessitates a selective packaging mechanism to ensure incorporation of a complete set of segments into virus particles. Packaging signals serve as segmen...

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Detalles Bibliográficos
Autores principales: White, Maria C., Tao, Hui, Steel, John, Lowen, Anice C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410869/
https://www.ncbi.nlm.nih.gov/pubmed/30760600
http://dx.doi.org/10.1073/pnas.1818494116