Cargando…

Tissue-specific BMAL1 cistromes reveal that rhythmic transcription is associated with rhythmic enhancer–enhancer interactions

The mammalian circadian clock relies on the transcription factor CLOCK:BMAL1 to coordinate the rhythmic expression of thousands of genes. Consistent with the various biological functions under clock control, rhythmic gene expression is tissue-specific despite an identical clockwork mechanism in ever...

Descripción completa

Detalles Bibliográficos
Autores principales: Beytebiere, Joshua R., Trott, Alexandra J., Greenwell, Ben J., Osborne, Collin A., Vitet, Helene, Spence, Jessica, Yoo, Seung-Hee, Chen, Zheng, Takahashi, Joseph S., Ghaffari, Noushin, Menet, Jerome S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411008/
https://www.ncbi.nlm.nih.gov/pubmed/30804225
http://dx.doi.org/10.1101/gad.322198.118