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Tissue-specific BMAL1 cistromes reveal that rhythmic transcription is associated with rhythmic enhancer–enhancer interactions
The mammalian circadian clock relies on the transcription factor CLOCK:BMAL1 to coordinate the rhythmic expression of thousands of genes. Consistent with the various biological functions under clock control, rhythmic gene expression is tissue-specific despite an identical clockwork mechanism in ever...
Autores principales: | Beytebiere, Joshua R., Trott, Alexandra J., Greenwell, Ben J., Osborne, Collin A., Vitet, Helene, Spence, Jessica, Yoo, Seung-Hee, Chen, Zheng, Takahashi, Joseph S., Ghaffari, Noushin, Menet, Jerome S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411008/ https://www.ncbi.nlm.nih.gov/pubmed/30804225 http://dx.doi.org/10.1101/gad.322198.118 |
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