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Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity

Synaptotagmin-11 (Syt11) is a Synaptotagmin isoform that lacks an apparent ability to bind calcium, phospholipids, or SNARE proteins. While human genetic studies have linked mutations in the Syt11 gene to schizophrenia and Parkinson's disease, the localization or physiological role of Syt11 rem...

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Detalles Bibliográficos
Autores principales: Shimojo, Masafumi, Madara, Joseph, Pankow, Sandra, Liu, Xinran, Yates, John, Südhof, Thomas C., Maximov, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411015/
https://www.ncbi.nlm.nih.gov/pubmed/30808661
http://dx.doi.org/10.1101/gad.320077.118