Increased Cystatin F Levels Correlate with Decreased Cytotoxicity of Cytotoxic T Cells

BACKGROUND: Cystatin F is a protein inhibitor of cysteine peptidases, expressed predominantly in immune cells and localised in endosomal/lysosomal compartments. In cytotoxic immune cells cystatin F inhibits both the major pro-granzyme convertases, cathepsins C and H that activate granzymes, and cath...

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Detalles Bibliográficos
Autores principales: Prunk, Mateja, Nanut, Milica Perisic, Sabotic, Jerica, Svajger, Urban, Kos, Janko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411024/
https://www.ncbi.nlm.nih.gov/pubmed/30840596
http://dx.doi.org/10.2478/raon-2019-0007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411024/
https://www.ncbi.nlm.nih.gov/pubmed/30840596
http://dx.doi.org/10.2478/raon-2019-0007

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