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Coupling S-adenosylmethionine–dependent methylation to growth: Design and uses
We present a selection design that couples S-adenosylmethionine–dependent methylation to growth. We demonstrate its use in improving the enzyme activities of not only N-type and O-type methyltransferases by 2-fold but also an acetyltransferase of another enzyme category when linked to a methylation...
Autores principales: | Luo, Hao, Hansen, Anne Sofie L., Yang, Lei, Schneider, Konstantin, Kristensen, Mette, Christensen, Ulla, Christensen, Hanne B., Du, Bin, Özdemir, Emre, Feist, Adam M., Keasling, Jay D., Jensen, Michael K., Herrgård, Markus J., Palsson, Bernhard O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411097/ https://www.ncbi.nlm.nih.gov/pubmed/30856169 http://dx.doi.org/10.1371/journal.pbio.2007050 |
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