Pan-cancer association of a centrosome amplification gene expression signature with genomic alterations and clinical outcome

Centrosome amplification (CA) is a common feature of human tumours and a promising target for cancer therapy. However, CA’s pan-cancer prevalence, molecular role in tumourigenesis and therapeutic value in the clinical setting are still largely unexplored. Here, we used a transcriptomic signature (CA...

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Detalles Bibliográficos
Autores principales: de Almeida, Bernardo P., Vieira, André F., Paredes, Joana, Bettencourt-Dias, Mónica, Barbosa-Morais, Nuno L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411098/
https://www.ncbi.nlm.nih.gov/pubmed/30856170
http://dx.doi.org/10.1371/journal.pcbi.1006832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411098/
https://www.ncbi.nlm.nih.gov/pubmed/30856170
http://dx.doi.org/10.1371/journal.pcbi.1006832

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