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The addition of a polyglutamate domain to the angiogenic QK peptide improves peptide coupling to bone graft materials leading to enhanced endothelial cell activation

Vascularization of bone grafts is vital for graft integration and bone repair, however non-autologous graft sources have limited potential to induce angiogenesis. Accordingly, intensive research has focused on functionalizing non-autologous materials with angiogenic factors. In the current study we...

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Detalles Bibliográficos
Autores principales: Pensa, Nicholas W., Curry, Andrew S., Reddy, Michael S., Bellis, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411101/
https://www.ncbi.nlm.nih.gov/pubmed/30856221
http://dx.doi.org/10.1371/journal.pone.0213592