Nicotinamide phosphoribosyltransferase expression and clinical outcome of resected stage I/II pancreatic ductal adenocarcinoma

BACKGROUND: Nicotinamide phosphoribosyltransferase (NAMPT) plays a key role in the biosynthesis of nicotinamide adenine dinucleotide (NAD(+)), which is a vital cofactor in redox reactions and a substrate for NAD(+) consuming enzymes including CD38, PARPs and sirtuins. NAMPT over-expression has been...

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Detalles Bibliográficos
Autores principales: Davis, Katelynn, Dunseth, Craig D., Mott, Sarah L., Cramer-Morales, Kimberly L., Miller, Ann M., Ear, Po Hien, Mezhir, James J., Bellizzi, Andrew M., Chan, Carlos H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411120/
https://www.ncbi.nlm.nih.gov/pubmed/30856230
http://dx.doi.org/10.1371/journal.pone.0213576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411120/
https://www.ncbi.nlm.nih.gov/pubmed/30856230
http://dx.doi.org/10.1371/journal.pone.0213576

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