Development of a high-throughput fluorescent no-wash sodium influx assay

Voltage-gated sodium channels (Na(V)s) are key therapeutic targets for pain, epilepsy and cardiac arrhythmias. Here we describe the development of a no-wash fluorescent sodium influx assay suitable for high-throughput screening and characterization of novel drug leads. Addition of red-violet food dy...

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Detalles Bibliográficos
Autores principales: Tay, Bryan, Stewart, Teneale A., Davis, Felicity M., Deuis, Jennifer R., Vetter, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411159/
https://www.ncbi.nlm.nih.gov/pubmed/30856233
http://dx.doi.org/10.1371/journal.pone.0213751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411159/
https://www.ncbi.nlm.nih.gov/pubmed/30856233
http://dx.doi.org/10.1371/journal.pone.0213751

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