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NDRG1 facilitates the replication and persistence of Kaposi’s sarcoma-associated herpesvirus by interacting with the DNA polymerase clamp PCNA

Kaposi’s sarcoma-associated herpesvirus (KSHV) latently infects host cells and establishes lifelong persistence as an extra-chromosomal episome in the nucleus. To persist in proliferating cells, the viral genome typically replicates once per cell cycle and is distributed into daughter cells. This pr...

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Detalles Bibliográficos
Autores principales: Zhang, Fang, Liang, Deguang, Lin, Xiaoxi, Zou, Zhe, Sun, Rui, Wang, Xing, Liang, Xiaozhen, Kaye, Kenneth M., Lan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411202/
https://www.ncbi.nlm.nih.gov/pubmed/30811506
http://dx.doi.org/10.1371/journal.ppat.1007628