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NDRG1 facilitates the replication and persistence of Kaposi’s sarcoma-associated herpesvirus by interacting with the DNA polymerase clamp PCNA
Kaposi’s sarcoma-associated herpesvirus (KSHV) latently infects host cells and establishes lifelong persistence as an extra-chromosomal episome in the nucleus. To persist in proliferating cells, the viral genome typically replicates once per cell cycle and is distributed into daughter cells. This pr...
Autores principales: | Zhang, Fang, Liang, Deguang, Lin, Xiaoxi, Zou, Zhe, Sun, Rui, Wang, Xing, Liang, Xiaozhen, Kaye, Kenneth M., Lan, Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411202/ https://www.ncbi.nlm.nih.gov/pubmed/30811506 http://dx.doi.org/10.1371/journal.ppat.1007628 |
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